Arsenal have received a huge injury blow ahead of their game against Southampton.
According to the Football London journalist Kaya Kaynak, William Saliba is unlikely to be available on Friday when the Gunners face the Saints.
Meanwhile, Arsenal have refused to rule out the possibility of the defender returning to action next Wednesday for the league game versus Pep Guardiola Manchester City.
Mikel Arteta's side are now leading the Premier League table, having just a four-point gap with the rivals City.
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