Ajax will be hosting Tottenham in the Champions League semi-finals second leg after winning the first leg with 1-0 score.
Ahead of the game, former Manchester United coach Jose Mourinho made his prediction.
"It's really, really hard (to call)," Mourinho said. "Looking to the history of the Champions League, Ajax are better away than at home.
"They've had three victories in England, Spain and Italy, they played against the top countries, even against Benfica, nothing was easy for them and they were magnificent.
"At home, as I was saying, they have their style of play but so do Tottenham and I think Tottenham knows that they also can [progress].
"To play without [Harry] Kane is difficult, to play without Kane and Son [Heung-min] at the same time is even more difficult and next time at least Son is there.
"He is an aggressive player, he's fast, he has transitions and he can hurt people so the game is open."
The game is scheduled at 8pm (BST) at Johan Cruyff Arena.