Manchester City trio John Stones, Fabian Delph and Nicolas Otamendi are all unavailable for the current international break.
Stones and Delph were both included in Gareth Southgate’s initial 25-man England squad for the Euro 202 qualifiers against the Czech Republic and Montenegro but the duo have been forced to withdraw due to their respective injuries.
Argentina international Otamendi is unavailable for the friendlies against Venezuela and Morocco with a minor ankle knock although he is expected to return to full fitness after the international break.
All three City players are set to return to domestic action when the Citizens travel to relegation-threatened Fulham on March 30.